Clinical Trials

Formal Study Name

Beamion BCGC-1: A Phase Ib Dose Escalation and Phase II Dose Optimization, Randomized, Open-label, Multicenter Trial of Oral Zongertinib (BI 1810631) Alone or in Combination With Other Agents for the Treatment of Patients With Advanced HER2+ Metastatic Breast Cancer (mBC), Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma (mGEAC), or Metastatic Colorectal Cancer (mCRC)

Histology

HER2+

Stage

4

Treatment Phase

1B

Trial Phase

1/2

Trial Type

Interventional

Principal Investigator

Philip Lammers, MD

Locations Where Open

• Baptist Cancer Center-Humphreys
• Baptist Cancer Center-Walnut Grove
• Baptist Cancer Center-Collierville
• Baptist Cancer Center - DeSoto

Formal Study Name

A Phase III, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Divarasib and Pembrolizumab Versus Pembrolizumab and Pemetrexed and Carboplatin or Cisplatin in Patients With Previously Untreated, KRAS G12C-Mutated, Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer

Histology

Non-small cell, Non-squamous

Treatment Phase

Advanced or Metastatic

Trial Phase

3

Trial Type

Interventional

Principal Investigator

Osa Ogbeide, MD

Locations Where Open

• Baptist Cancer Center-Humphreys
• Baptist Cancer Center-Walnut Grove
• Baptist Cancer Center-Memphis Thoracic Multidisciplinary Care
• Baptist Cancer Center-Bartlett
• Baptist Cancer Center-Collierville
• Baptist Cancer Center - DeSoto

Formal Study Name

Immune Checkpoint Inhibitor Toxicity (I-CHECKIT): A Prospective Observational Study

Histology

Triple Negative (ER-, PR-, HER2-)

Treatment Phase

Neoadjuvant or Advanced

Trial Type

Observational

Principal Investigator

Elizabeth John

Locations Where Open

• Baptist Cancer Center-Humphreys
• Baptist Cancer Center-Walnut Grove
• Baptist Cancer Center-Memphis Thoracic Multidisciplinary Care
• Baptist Cancer Center-Bartlett
• Baptist Cancer Center-Collierville
• Baptist Cancer Center - DeSoto
• Baptist Cancer Center-Grenada
• Baptist Cancer Center- Golden Triangle Columbus

Formal Study Name

Five or Ten Year Colonoscopy for 1-2 Non-Advanced Adenomatous Polyps

Trial Type

Interventional

Principal Investigator

Abdullah Al-Rashdan, MD

Locations Where Open

• Baptist Cancer Center-Humphreys

Formal Study Name

Phase II Study of Cytarabine + Daunorubicin (7 + 3) + Gemtuzumab Ozogamicin vs. Cytarabine + Daunorubicin (7 + 3) + Venetoclax for the Treatment of Newly Diagnosed Core Binding Factor Acute Myeloid Leukemia (CBF-AML) in Younger Adults: A MyeloMATCH Substudy

Histology

Acute Myeloid Leukemia

Trial Phase

2

Trial Type

Interventional

Principal Investigator

Salil Goorha, MD

Locations Where Open

• Baptist Cancer Center-Humphreys
• Baptist Cancer Center-Walnut Grove
• Baptist Cancer Center-Bartlett
• Baptist Cancer Center-Collierville
• Baptist Cancer Center - DeSoto
• Baptist Cancer Center-Grenada
• Baptist Cancer Center- Golden Triangle Columbus

Formal Study Name

Phase III Evaluation of Fixed Duration Zanubrutinib Plus Sonrotoclax-Based Therapy Compared to Continuous Zanubrutinib in Previously Untreated Older Patients With Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL)

Histology

Chronic Lymphocytic Leukemia or Small Lymphocytic Leukemia

Trial Phase

3

Trial Type

Interventional

Principal Investigator

Muhammad Raza, MD

Locations Where Open

• Baptist Cancer Center-Humphreys
• Baptist Cancer Center-Bartlett
• Baptist Cancer Center-Collierville
• Baptist Cancer Center - DeSoto
• Baptist Cancer Center-Walnut Grove

Formal Study Name

A Phase 3, Randomized, Double-blind, Placebo- and Active-Comparator-Controlled Clinical Study of Adjuvant V940 (mRNA-4157) Plus Pembrolizumab Versus Adjuvant Placebo Plus Pembrolizumab in Participants With Resected Stage II, IIIA, IIIB (N2) Non-small Cell Lung Cancer (INTerpath-002)

Histology

NSCLC

Stage

2-3B

Treatment Phase

Adjuvant

Trial Phase

3

Trial Type

Interventional

Principal Investigator

Philip Lammers

Locations Where Open

• Baptist Cancer Center-Humphreys
• Baptist Cancer Center-Walnut Grove
• Baptist Cancer Center-Memphis Thoracic Multidisciplinary Care
• Baptist Cancer Center-Bartlett

Formal Study Name

Short TeRm Intensified Pembrolizumab (KEytruda) and Tivozanib for High-Risk Renal Cell Carcinoma - STRIKE

Histology

Clear Cell Renal Cell Carcinoma

Stage

2 to 3

Treatment Phase

Adjuvant

Trial Phase

3

Trial Type

Interventional

Principal Investigator

Osa Ogbeide, MD

Locations Where Open

• Baptist Cancer Center-Humphreys
• Baptist Cancer Center-Bartlett
• Baptist Cancer Center-Collierville
• Baptist Cancer Center - DeSoto
• Baptist Cancer Center-Grenada
• Baptist Cancer Center- Golden Triangle Columbus

Formal Study Name

A Phase 2, Multicenter, Open-Label Study of CC-97540 (BMS-986353), CD19-Targeted NEX-T CAR T Cells, in Participants With Active SLE (Including Lupus Nephritis) With Inadequate Response to Glucocorticoids and at Least 2 Immunosuppressants (Breakfree-SLE)

Treatment Phase

Refractory

Trial Phase

2

Trial Type

Interventional

Principal Investigator

Sharon Dowell, MD

Locations Where Open

• Baptist Cancer Center-Walnut Grove
• NEA Baptist Fowler Family Center for Cancer Care

Formal Study Name

Phase Ib Study of Eltanexor and Venetoclax in Relapsed or Refractory Myelodysplastic Syndrome and Acute Myeloid Leukemia

Histology

Acute Myeloid Leukemia or Myelodysplastic Syndrome

Treatment Phase

Refractory or Relapsed

Trial Phase

1

Trial Type

Interventional

Principal Investigator

Salil Goorha, MD

Locations Where Open

• Baptist Cancer Center-Memphis Malignant Hematology & Stem Cell Clinic